HitPredict

Interactor 1: H31 (P68433)
Histone H3.1
Gene: H3c1

Interactor 2: CBX1 (P83917)
Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein)
Gene: CBX1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	16547356, 11882902
Identification Methods	pull down, classical fluorescence spectroscopy, nuclear magnetic resonance
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 185
+	Hs
		934721 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		1027017 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		934657 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		949795 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800341 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		800397 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		203659 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		327837 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18
+	Hs
		327844 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18
+	Hs
		935237 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV92_HUMAN (13-121): 2.75e-28: 110: 28.18
+	Hs
		316000 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		934768 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		935387 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		1059154 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		316040 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		123231 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		123254 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		935259 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		934987 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL2_HUMAN (17-122): 5.86e-24: 99.4: 28.44
+	Hs
		1086221 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CDYL2_HUMAN (17-122): 5.86e-24: 99.4: 28.44