HitPredict

Interactor 1: NECP1 (P69682)
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)
Gene: Necap1

Interactor 2: Q66HM2 (Q66HM2)
AP-2 complex subunit alpha
Gene: Ap2a2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17762867
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~DUF1681
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 277 Rn			1 939
+	Mm
		567534 NECP1_MOUSE (1-277): 8.75e-163: 454: 97.11		AP2A2_MOUSE (1-939): 0: 889: 99.57
+	Hs
		302186 NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Hs
		321598 NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Rn
		88761 NECP1_RAT (1-277): 2.28e-158: 443: 100.00		D3ZUY8_RAT (1-939): 0: 836: 81.25
+	Hs
		302215 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Hs
		321655 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Hs
		925949 NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		1014052 NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Hs
		212648 NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42		AP1G1_HUMAN (1-824): 0: 599: 24.91
+	Hs
		926024 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		1014091 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Hs
		212666 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP1G1_HUMAN (1-824): 0: 599: 24.91