HitPredict

Interactor 1: DID2 (P69771)
Vacuolar protein-sorting-associated protein 46 (Charged multivesicular body protein 1) (DOA4-independent degradation protein 2) (Fifty two inhibitor 1)
Gene: DID2

Interactor 2: VPS60 (Q03390)
Vacuolar protein-sorting-associated protein 60 (Charged multivesicular body protein 5)
Gene: VPS60

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	31273031, 35445263, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0005737 - cytoplasm GO:0005771 - multivesicular body GO:0015031 - protein transport GO:0032511 - late endosome to vacuole transport via multivesicular body sorting pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 204 Sc			1 229
+	Ce
		1090380 Q9U2F6_CAEEL (3-184): 4.67e-46: 153: 20.77		Q18886_CAEEL (2-222): 2.41e-42: 144: 19.46
+	Hs
		1349478 CHMP3_HUMAN (3-204): 2.43e-43: 146: 13.15		CHMP5_HUMAN (1-225): 7.1e-43: 146: 28.44
+	At
		1276050 VPS2C_ARATH (4-203): 5.77e-48: 157: 22.77		VP322_ARATH (1-227): 5e-38: 133: 19.30
+	Dm
		1373131 Q9VRJ5_DROME (4-204): 6.57e-43: 144: 17.33		CHMP5_DROME (1-228): 9.42e-43: 145: 27.19
+	Sc
		732860 DID4_YEAST (4-203): 4.54e-43: 146: 18.89		VPS60_YEAST (1-229): 6.19e-42: 143: 100.00
+	Dm
		1371192 Q9VN02_DROME (2-204): 3.38e-42: 143: 13.49		CHMP5_DROME (1-228): 9.42e-43: 145: 27.19
+	At
		287069 VPS2C_ARATH (4-203): 5.77e-48: 157: 22.77		VP321_ARATH (1-220): 8.32e-36: 127: 16.82
+	Hs
		1316088 CHMP3_HUMAN (3-204): 2.43e-43: 146: 13.15		CHM4A_HUMAN (1-229): 8.6e-38: 133: 18.34
+	Hs
		1330574 CHMP3_HUMAN (3-204): 2.43e-43: 146: 13.15		CHM4B_HUMAN (15-220): 3.6e-38: 133: 19.42
+	Dm
		1249820 Q9VRJ5_DROME (4-204): 6.57e-43: 144: 17.33		CHM4_DROME (2-222): 5.59e-38: 133: 17.78
+	Dm
		1249819 Q9VN02_DROME (2-204): 3.38e-42: 143: 13.49		CHM4_DROME (2-222): 5.59e-38: 133: 17.78
+	At
		1209623 VPS2C_ARATH (4-203): 5.77e-48: 157: 22.77		VP201_ARATH (1-228): 6.9e-32: 117: 19.30
+	At
		1276045 VPS2C_ARATH (4-203): 5.77e-48: 157: 22.77		VP202_ARATH (1-228): 8.39e-31: 114: 20.44
+	Sc
		732845 DID4_YEAST (4-203): 4.54e-43: 146: 18.89		SNF7_YEAST (4-226): 1.29e-34: 125: 20.98
+	At
		287066 VPS2B_ARATH (4-203): 6.03e-42: 142: 17.45		VP321_ARATH (1-220): 8.32e-36: 127: 16.82
+	Sc
		732861 DID4_YEAST (4-203): 4.54e-43: 146: 18.89		VPS20_YEAST (6-227): 1.29e-33: 122: 17.12
+	At
		1013147 CHM1A_ARATH (5-204): 4.16e-47: 155: 35.82		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90
+	At
		1013164 VPS2A_ARATH (3-203): 5.95e-47: 155: 21.03		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90
+	At
		1013166 CHM1B_ARATH (5-204): 1.8e-42: 143: 36.82		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90
+	At
		1013141 VPS2B_ARATH (4-203): 6.03e-42: 142: 17.45		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90