Interactor 1: SIX5 (P70178)
Homeobox protein SIX5 (DM locus-associated homeodomain protein homolog) (Sine oculis homeobox homolog 5)
Gene: SIX5

Interactor 2: SRF (Q9JM73)
Serum response factor (SRF)
Gene: SRF

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 15102471
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~SRF-TF
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 719
Mm

1 504
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024