Interactor 1: TRAF5 (P70191)
TNF receptor-associated factor 5
Gene: TRAF5

Interactor 2: CIKS (Q8N7N6)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: Traf3ip2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 21822258, 21822257
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0023019 - signal transduction involved in regulation of gene expression
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0048255 - mRNA stabilization
GO:0070534 - protein K63-linked ubiquitination
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 558
Mm

1 555
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024