HitPredict

Interactor 1: TRAF5 (P70191)
TNF receptor-associated factor 5
Gene: TRAF5

Interactor 2: MAVS (Q8VCF0)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23951545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 558 Mm			1 503
+	Hs
		129573 TRAF5_HUMAN (1-558): 1.55e-150: 445: 79.57		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Mm
		1141429 TRAF3_MOUSE (7-557): 3.31e-119: 365: 41.91		MAVS_MOUSE (1-503): 2.16e-61: 211: 100.00
+	Hs
		1024700 TRAF3_HUMAN (7-557): 2.72e-120: 368: 41.65		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Mm
		761831 TRAF2_MOUSE (13-555): 4.65e-106: 329: 30.02		MAVS_MOUSE (1-503): 2.16e-61: 211: 100.00
+	Hs
		1020764 TRAF2_HUMAN (13-555): 4e-106: 329: 28.57		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Mm
		936265 TRAF6_MOUSE (21-552): 5.7e-82: 267: 23.05		MAVS_MOUSE (1-503): 2.16e-61: 211: 100.00
+	Mm
		1112453 Q3UCL2_MOUSE (36-468): 1.67e-82: 266: 10.81		MAVS_MOUSE (1-503): 2.16e-61: 211: 100.00
+	Hs
		1190136 TRAF6_HUMAN (21-552): 3.48e-80: 262: 22.86		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1023708 TRAF1_HUMAN (161-553): 1.45e-80: 260: 31.49		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		584997 RO52_HUMAN (39-468): 8.44e-78: 254: 10.93		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1190083 TRIM7_HUMAN (40-469): 1.68e-62: 215: 11.30		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1052694 TRI25_HUMAN (38-403): 5.19e-49: 181: 16.01		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1190082 TRI31_HUMAN (34-366): 1.4e-49: 178: 14.71		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		537122 TRI27_HUMAN (32-469): 8.22e-72: 240: 11.57		MAGL2_HUMAN (57-493): 3.47e-09: 61.7: 10.68
+	Hs
		1190047 RN166_HUMAN (36-171): 6.58e-13: 70.3: 25.36		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1190056 RN125_HUMAN (37-172): 3.31e-12: 68.4: 23.18		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93