Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 17709375, 28993672, 15147900, 21460221, 19465916
Identification Methods enzymatic study, affinity chromatography technology, two hybrid, comigration in non denaturing gel electrophoresis, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000045 - autophagosome assembly
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0001503 - ossification
GO:0001701 - in utero embryonic development
and 66 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 530
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Last updated: 15 Jul 2024