HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: NLRX1 (Q3TL44)
NLR family member X1
Gene: NLRX1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	21703539, 21703540
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Mm			1 975
+	Hs
		1200102 TRAF6_HUMAN (1-530): 1.18e-143: 425: 87.93		NLRX1_HUMAN (1-974): 0: 720: 90.25
+	Mm
		1111982 TRAF3_MOUSE (14-510): 9.77e-92: 293: 21.64		NLRX1_MOUSE (1-975): 0: 734: 100.00
+	Hs
		1024702 TRAF3_HUMAN (14-510): 1.85e-90: 290: 20.94		NLRX1_HUMAN (1-974): 0: 720: 90.25
+	Hs
		1335704 TRAF6_HUMAN (1-530): 1.18e-143: 425: 87.93		NOD2_HUMAN (115-932): 7.1e-128: 414: 19.45
+	Hs
		1313362 TRAF4_HUMAN (54-515): 6.05e-94: 295: 25.68		NOD2_HUMAN (115-932): 7.1e-128: 414: 19.45
+	Hs
		1313386 TRAF4_HUMAN (54-515): 6.05e-94: 295: 25.68		NOD1_HUMAN (63-933): 6.87e-125: 404: 16.65
+	Hs
		1223391 TRI22_HUMAN (56-423): 3.57e-49: 178: 13.88		NOD2_HUMAN (115-932): 7.1e-128: 414: 19.45
+	Hs
		537077 TRI27_HUMAN (56-385): 9.43e-39: 150: 11.87		NOD2_HUMAN (115-932): 7.1e-128: 414: 19.45
+	Hs
		135016 TRI38_HUMAN (56-417): 1.34e-40: 154: 10.81		NLRP6_HUMAN (10-867): 6.3e-127: 408: 20.02
+	Hs
		1202836 TRI31_HUMAN (57-384): 1.36e-41: 156: 14.71		NAL10_HUMAN (68-592): 2.54e-107: 349: 18.76
+	Hs
		1186106 TRAF6_HUMAN (1-530): 1.18e-143: 425: 87.93		NLRC3_HUMAN (400-780): 1.52e-12: 74: 13.20
+	Hs
		886400 TRI25_HUMAN (63-387): 4.89e-43: 164: 13.39		NAL12_HUMAN (515-855): 1.38e-29: 129: 17.58
+	Hs
		1052765 TRI25_HUMAN (63-387): 4.89e-43: 164: 13.39		NLRP1_HUMAN (792-970): 8.57e-22: 104: 21.08
+	Mm
		1207564 TRI47_MOUSE (68-358): 3.2e-45: 170: 15.63		NLRP3_MOUSE (522-807): 1.88e-18: 93.3: 13.69
+	Hs
		1149907 TRI68_HUMAN (57-417): 2.56e-42: 159: 12.96		NLRP1_HUMAN (792-970): 8.57e-22: 104: 21.08
+	Hs
		1299025 TRI31_HUMAN (57-384): 1.36e-41: 156: 14.71		NLRP3_HUMAN (538-812): 6.17e-20: 97.9: 15.66
+	Mm
		1112452 Q3UCL2_MOUSE (60-417): 8e-43: 160: 14.01		NLRP3_MOUSE (522-807): 1.88e-18: 93.3: 13.69
+	Hs
		301583 TRI37_HUMAN (56-519): 8.78e-49: 183: 14.83		RINI_HUMAN (639-813): 5.61e-11: 68: 17.46
+	Hs
		702498 TRI22_HUMAN (56-423): 3.57e-49: 178: 13.88		C2TA_HUMAN (823-932): 6.01e-12: 72.1: 18.97
+	Hs
		702485 TRI26_HUMAN (56-437): 1.12e-40: 156: 15.08		C2TA_HUMAN (823-932): 6.01e-12: 72.1: 18.97