HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: IRAK3 (Q8K4B2)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 21098228, 15102471, 23376919
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0019221 - cytokine-mediated signaling pathway
GO:0070498 - interleukin-1-mediated signaling pathway
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 530
Mm

1 609
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Mm
+ Mm

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Last updated: 15 Jul 2024