HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: CIKS (Q8N7N6)
E3 ubiquitin ligase TRAF3IP2 (EC 2.3.2.27) (Adapter protein CIKS) (Connection to IKK and SAPK/JNK) (E3 ubiquitin-protein ligase CIKS) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2)
Gene: Traf3ip2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 22649194, 15102471, 21822257
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0006955 - immune response
GO:0016567 - protein ubiquitination
GO:0019221 - cytokine-mediated signaling pathway
and 6 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 530
Mm

1 555
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024