Interactor 1: MP2K6 (P70236)
Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (SAPKK3)
Gene: Map2k6

Interactor 2: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21606198
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0001649 - osteoblast differentiation
GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 334
Mm

1 579
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+ Dm
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Last updated: 15 Jul 2024