HitPredict

Interactor 1: SMAD1 (P70340)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1)
Gene: SMAD1

Interactor 2: BTG2 (Q04211)
Protein BTG2 (BTG family member 2) (NGF-inducible protein TIS21)
Gene: BTG2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15542835
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Mm			1 158
+	Hs
		841388 SMAD1_HUMAN (1-465): 0: 653: 99.14		TOB1_HUMAN (9-123): 8.46e-57: 182: 42.61
+	Mm
		978996 SMAD9_MOUSE (3-465): 0: 575: 76.51		BTG2_MOUSE (1-158): 1.33e-89: 259: 100.00
+	Hs
		841398 SMAD5_HUMAN (2-465): 0: 618: 89.25		TOB1_HUMAN (9-123): 8.46e-57: 182: 42.61
+	Hs
		171372 SMAD9_HUMAN (3-465): 0: 609: 80.22		TOB1_HUMAN (9-123): 8.46e-57: 182: 42.61
+	Dm
		60229 MAD_DROME (2-465): 0: 585: 74.14		A4V4L0_DROME (9-125): 1.18e-48: 165: 40.17
+	Dr
		1186359 Q8AY15_DANRE (5-465): 0: 556: 60.13		Q7SZP8_DANRE (9-123): 1.58e-56: 181: 40.87
+	Hs
		841379 SMAD3_HUMAN (3-465): 0: 554: 59.44		TOB1_HUMAN (9-123): 8.46e-57: 182: 42.61
+	Dr
		1186362 Q8AY15_DANRE (5-465): 0: 556: 60.13		Q7SZR1_DANRE (9-123): 5.32e-56: 179: 40.87
+	Dr
		1186360 Q8AY16_DANRE (5-465): 0: 549: 59.48		Q7SZP8_DANRE (9-123): 1.58e-56: 181: 40.87
+	Dr
		1186363 Q8AY16_DANRE (5-465): 0: 549: 59.48		Q7SZR1_DANRE (9-123): 5.32e-56: 179: 40.87
+	Hs
		841384 SMAD4_HUMAN (8-454): 1.16e-150: 441: 33.15		TOB1_HUMAN (9-123): 8.46e-57: 182: 42.61