HitPredict

Interactor 1: E9Q6A7 (E9Q6A7)
Bromodomain PHD finger transcription factor
Gene: Bptf

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23395962, 23892456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2921 Mm			1 305
+	Mm
		56838 A2A654_MOUSE (1-636): 4.6e-141: 499: 99.84		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Hs
		641391 BPTF_HUMAN (45-692): 9.06e-145: 511: 79.82		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Mm
		1194645 BRD8_MOUSE (2172-2918): 2.64e-57: 219: 15.24		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Mm
		88353 D3YZC7_MOUSE (2244-2918): 3.3e-52: 202: 15.12		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Hs
		170479 TIF1A_HUMAN (2337-2916): 7.68e-41: 168: 15.67		NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72
+	Hs
		1334444 TRI33_HUMAN (2346-2917): 2.36e-38: 160: 13.40		NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72
+	Hs
		170302 TIF1A_HUMAN (2337-2916): 7.68e-41: 168: 15.67		LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49
+	Hs
		170262 TIF1A_HUMAN (2337-2916): 7.68e-41: 168: 15.67		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		170297 TIF1A_HUMAN (2337-2916): 7.68e-41: 168: 15.67		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Hs
		822656 KAT2B_HUMAN (2805-2905): 1.86e-40: 165: 46.54		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Hs
		1315222 CECR2_HUMAN (2805-2899): 1.15e-13: 79.7: 42.11		NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72
+	Hs
		170178 TIF1A_HUMAN (2337-2916): 7.68e-41: 168: 15.67		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08
+	Hs
		999101 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72
+	Mm
		788278 BAZ1B_MOUSE (405-452): 5.82e-12: 74.3: 41.18		NKX25_MOUSE (13-216): 2.84e-33: 126: 22.41
+	Hs
		620147 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81
+	Hs
		679102 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		256392 PHF2_HUMAN (2743-2799): 4.21e-10: 67.8: 47.37		LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49
+	Hs
		641388 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		999015 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		PITX2_HUMAN (52-296): 7.2e-30: 116: 16.05
+	Hs
		211845 EP300_HUMAN (2061-2628): 5.81e-09: 64.3: 12.32		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08