Interactor 1: EZH1 (P70351)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1
Interactor 2: SUZ12 (Q80U70)
Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)
Gene: SUZ12
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.71 | 1.00 | 0.847 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRC2_HTH_1~VEFS-Box, VEFS-Box~preSET_CXC, SET~VEFS-Box |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0035098 - ESC/E(Z) complex GO:0140718 - facultative heterochromatin formation |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
