Interactor 1: BID (P70444)
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
Gene: BID

Interactor 2: MCL1 (P97287)
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1)
Gene: MCL1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 18589438
Identification Methods isothermal titration calorimetry
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BID~Bcl-2
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0016020 - membrane
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 195
Mm

1 331
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024