Interactor 1: BID (P70444)
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
Gene: BID
Interactor 2: B2LA1 (Q07440)
Bcl-2-related protein A1 (A1-A) (Hemopoietic-specific early response protein) (Protein BFL-1)
Gene: Bcl2a1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.692 |
The method score is based on:
Property | Details |
---|---|
Experiments | 18462686 |
Identification Methods | isothermal titration calorimetry, x-ray crystallography |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | BID~Bcl-2 |
Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005741 - mitochondrial outer membrane GO:0043065 - positive regulation of apoptotic process |
Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024