HitPredict

Interactor 1: 4EBP2 (P70445)
Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2) (Phosphorylated heat- and acid-stable protein regulated by insulin 2) (PHAS-II)
Gene: Eif4ebp2

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16798736
Identification Methods	in-gel kinase assay
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031929 - TOR signaling GO:0035176 - social behavior
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 120 Mm			1 2549
+	Hs
		787478 4EBP2_HUMAN (1-120): 4.73e-62: 186: 95.00		MTOR_HUMAN (1-2549): 0: 2106: 98.94
+	Hs
		787477 4EBP1_HUMAN (4-120): 3.56e-51: 159: 57.98		MTOR_HUMAN (1-2549): 0: 2106: 98.94
+	Rn
		787620 4EBP1_RAT (4-120): 2.3e-52: 162: 59.32		MTOR_RAT (1-2549): 0: 2088: 99.49
+	Dm
		1369192 4EBP_DROME (1-120): 2.6e-34: 116: 38.02		TOR_DROME (17-2549): 0: 1809: 53.52
+	Hs
		1031514 4EBP1_HUMAN (4-120): 3.56e-51: 159: 57.98		ATM_HUMAN (270-2548): 0: 924: 14.32
+	Hs
		944228 4EBP1_HUMAN (4-120): 3.56e-51: 159: 57.98		PRKDC_HUMAN (724-2548): 0: 756: 14.35
+	Dm
		1211964 4EBP_DROME (1-120): 2.6e-34: 116: 38.02		TRA1_DROME (77-2548): 0: 679: 12.76
+	Hs
		236383 4EBP3_HUMAN (29-120): 6.76e-34: 114: 57.61		CAND1_HUMAN (22-1310): 5.06e-148: 498: 12.23