HitPredict

Interactor 1: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Interactor 2: RNF41 (Q8BH75)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	19483718
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 419 Mm			1 317
+	Hs
		584964 IRF3_HUMAN (1-417): 0: 524: 71.06		RO52_HUMAN (3-295): 1.95e-61: 204: 16.94
+	Mm
		936903 IRF3_MOUSE (1-419): 0: 560: 100.00		TRI26_MOUSE (3-301): 1.84e-42: 155: 12.14
+	Hs
		1019304 IRF3_HUMAN (1-417): 0: 524: 71.06		TRI26_HUMAN (3-301): 1.09e-51: 180: 12.62
+	Hs
		1056464 IRF3_HUMAN (1-417): 0: 524: 71.06		TRIM7_HUMAN (13-277): 1.6e-43: 157: 14.78
+	Hs
		584953 IRF5_HUMAN (2-414): 1.18e-154: 448: 27.04		RO52_HUMAN (3-295): 1.95e-61: 204: 16.94
+	Hs
		1056477 IRF3_HUMAN (1-417): 0: 524: 71.06		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		1024676 IRF3_HUMAN (1-417): 0: 524: 71.06		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78
+	Hs
		584932 IRF8_HUMAN (7-380): 2.33e-138: 404: 26.82		RO52_HUMAN (3-295): 1.95e-61: 204: 16.94
+	Hs
		135022 IRF8_HUMAN (7-380): 2.33e-138: 404: 26.82		TRI38_HUMAN (3-295): 3.42e-52: 180: 16.56
+	Hs
		1039479 IRF5_HUMAN (2-414): 1.18e-154: 448: 27.04		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Hs
		585026 IRF7_HUMAN (4-376): 1.83e-121: 363: 25.60		RO52_HUMAN (3-295): 1.95e-61: 204: 16.94
+	Mm
		619049 IRF8_MOUSE (7-380): 8.09e-139: 405: 26.45		TRI26_MOUSE (3-301): 1.84e-42: 155: 12.14
+	Hs
		1071083 IRF4_HUMAN (7-391): 3.75e-148: 429: 27.64		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		880598 IRF5_MOUSE (2-414): 1.28e-146: 427: 27.04		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Mm
		618926 IRF8_MOUSE (7-380): 8.09e-139: 405: 26.45		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Hs
		971763 IRF8_HUMAN (7-380): 2.33e-138: 404: 26.82		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		936217 IRF7_MOUSE (2-376): 3.98e-131: 386: 28.88		TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85
+	Hs
		1273358 IRF7_HUMAN (4-376): 1.83e-121: 363: 25.60		TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75
+	Mm
		619079 IRF8_MOUSE (7-380): 8.09e-139: 405: 26.45		RN114_MOUSE (11-107): 8.85e-10: 59.7: 29.59
+	Hs
		501044 IRF1_HUMAN (1-200): 1.56e-65: 214: 27.67		TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78