Interactor 1: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3
Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 0.60 | 0.561 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21862579 |
| Identification Methods | affinity chromatography technology, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway GO:0005829 - cytosol GO:0010468 - regulation of gene expression GO:0032727 - positive regulation of interferon-alpha production GO:0032728 - positive regulation of interferon-beta production and 3 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
