HitPredict

Interactor 1: MACA (P75830)
Macrolide export protein MacA
Gene: MACA

Interactor 2: MACA (P75830)
Macrolide export protein MacA
Gene: MACA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.812

The method score is based on:

Property	Details
Experiments	19805313, 19254725
Identification Methods	cross-linking study, surface plasmon resonance, x-ray crystallography, molecular sieving
Interaction Type	direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	HlyD_D23~HlyD_D23
Common GO terms	GO:0005886 - plasma membrane GO:0015562 - efflux transmembrane transporter activity GO:0016020 - membrane GO:0019898 - extrinsic component of membrane GO:0046677 - response to antibiotic and 3 others more... GO:1990196 - MacAB-TolC complex GO:1990281 - efflux pump complex GO:1990961 - xenobiotic detoxification by transmembrane export across the plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	371
Ec

1	371

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024