HitPredict

Interactor 1: ARNA (P77398)
Bifunctional polymyxin resistance protein ArnA (Polymyxin resistance protein PmrI) [Includes: UDP-4-amino-4-deoxy-L-arabinose formyltransferase (EC 2.1.2.13) (ArnAFT) (UDP-L-Ara4N formyltransferase); UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating (EC 1.1.1.305) (ArnADH) (UDP-GlcUA decarboxylase) (UDP-glucuronic acid dehydrogenase)]
Gene: ARNA

Interactor 2: ARNA (P77398)
Bifunctional polymyxin resistance protein ArnA (Polymyxin resistance protein PmrI) [Includes: UDP-4-amino-4-deoxy-L-arabinose formyltransferase (EC 2.1.2.13) (ArnAFT) (UDP-L-Ara4N formyltransferase); UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating (EC 1.1.1.305) (ArnADH) (UDP-GlcUA decarboxylase) (UDP-glucuronic acid dehydrogenase)]
Gene: ARNA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 15939024
Identification Methods molecular sieving, light scattering, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Epimerase~Epimerase, Epimerase~Formyl_trans_C, Formyl_trans_C~Formyl_trans_C, Formyl_trans_C~Formyl_trans_N, Formyl_trans_N~Formyl_trans_N
Common GO terms GO:0009103 - lipopolysaccharide biosynthetic process
GO:0009245 - lipid A biosynthetic process
GO:0032991 - protein-containing complex
GO:0033320 - UDP-D-xylose biosynthetic process
GO:0046677 - response to antibiotic
and 5 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 660
Ec

1 660
+ Hs
+ Dr
+ At
+ Ec
+ At
+ Hs
+ At
+ Dm
+ Cj
+ Ec
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024