HitPredict

Interactor 1: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Interactor 2: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22889411
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 690
+	Mm
		956922 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX2_MOUSE (1-690): 1.46e-138: 424: 89.73
+	Hs
		940504 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Mm
		250614 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX1_MOUSE (16-690): 3.38e-117: 369: 44.90
+	Hs
		1252410 ROBO3_HUMAN (11-362): 1.58e-30: 125: 12.57		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Hs
		1252373 NRCAM_HUMAN (1-365): 3.3e-22: 100: 11.03		LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07
+	Mm
		250622 HECAM_MOUSE (19-360): 1.27e-23: 102: 18.77		LNX1_MOUSE (16-690): 3.38e-117: 369: 44.90
+	Hs
		940411 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		DLG1_HUMAN (314-690): 1.08e-30: 130: 16.15
+	Hs
		940410 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73
+	Hs
		940506 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		940421 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		SCRIB_HUMAN (215-592): 4.05e-12: 72: 11.68
+	Hs
		940533 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		MAGI1_HUMAN (558-670): 1.23e-10: 67.1: 25.83
+	Mm
		292319 JAM1_MOUSE (3-305): 2.07e-48: 167: 20.32		MPDZ_MOUSE (317-685): 1.35e-27: 122: 16.85
+	Mm
		936319 DCC_MOUSE (1-365): 1.86e-36: 142: 12.88		DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07
+	Mm
		1195001 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG1_MOUSE (306-689): 1.67e-38: 155: 21.85
+	Rn
		1337448 JAM1_RAT (3-305): 6.26e-50: 171: 20.00		PARD3_RAT (473-672): 2.44e-15: 82.4: 29.13
+	Mm
		1143386 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07
+	Hs
		1256876 JAM3_HUMAN (18-296): 2.7e-46: 162: 18.79		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		883798 JAM2_HUMAN (26-296): 8.44e-42: 149: 20.78		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13
+	Hs
		1136434 NRCAM_HUMAN (1-365): 3.3e-22: 100: 11.03		MAGI3_HUMAN (279-684): 3.5e-13: 75.4: 12.90
+	Hs
		1256929 JAM1_HUMAN (148-320): 1.14e-13: 72.7: 15.35		PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13