HitPredict

Interactor 1: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22889411
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 728
+	Mm
		250614 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX1_MOUSE (1-728): 8.14e-134: 414: 87.98
+	Hs
		940491 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		LNX2_HUMAN (3-728): 5.7e-116: 366: 45.21
+	Mm
		956922 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX2_MOUSE (1-728): 4.94e-115: 364: 45.62
+	Hs
		1252410 ROBO3_HUMAN (11-362): 1.58e-30: 125: 12.57		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252373 NRCAM_HUMAN (1-365): 3.3e-22: 100: 11.03		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Mm
		250622 HECAM_MOUSE (19-360): 1.27e-23: 102: 18.77		LNX1_MOUSE (1-728): 8.14e-134: 414: 87.98
+	Hs
		940506 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		940411 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Hs
		940410 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		PTN13_HUMAN (455-725): 4.02e-23: 107: 15.44
+	Hs
		940421 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Rn
		1337448 JAM1_RAT (3-305): 6.26e-50: 171: 20.00		PARD3_RAT (204-552): 2.96e-33: 139: 18.61
+	Mm
		292319 JAM1_MOUSE (3-305): 2.07e-48: 167: 20.32		MPDZ_MOUSE (262-711): 2.29e-33: 140: 14.07
+	Hs
		1256876 JAM3_HUMAN (18-296): 2.7e-46: 162: 18.79		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		883798 JAM2_HUMAN (26-296): 8.44e-42: 149: 20.78		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Mm
		936319 DCC_MOUSE (1-365): 1.86e-36: 142: 12.88		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Mm
		1195001 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG1_MOUSE (331-728): 7.2e-29: 125: 17.16
+	Mm
		1143386 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		1256929 JAM1_HUMAN (148-320): 1.14e-13: 72.7: 15.35		PARD3_HUMAN (247-554): 1.39e-32: 137: 20.96
+	Hs
		1136434 NRCAM_HUMAN (1-365): 3.3e-22: 100: 11.03		MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75
+	Hs
		1050029 LRIG1_HUMAN (18-136): 4.76e-10: 63: 16.81		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52