HitPredict

Interactor 1: F1LP82 (F1LP82)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: Rab2a

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005525 - GTP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Rn			1 1383
+	Rn
		69428 B0BMW0_RAT (2-190): 9.83e-87: 256: 56.77		INSR_RAT (1-1383): 0: 1575: 100.00
+	Rn
		102471 G3V6H0_RAT (2-192): 8.54e-85: 250: 42.27		INSR_RAT (1-1383): 0: 1575: 100.00
+	Rn
		544805 RB11A_RAT (2-196): 2.19e-81: 242: 43.35		INSR_RAT (1-1383): 0: 1575: 100.00
+	Hs
		411350 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		INSR_HUMAN (27-1383): 0: 1527: 95.43
+	Hs
		435598 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		665570 RAB2A_HUMAN (2-187): 1.8e-83: 248: 89.95		EPHB2_HUMAN (662-1317): 0: 577: 23.01
+	Hs
		895087 RAB2A_HUMAN (2-187): 1.8e-83: 248: 89.95		EPHA7_HUMAN (664-1321): 0: 568: 22.55
+	Hs
		665466 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		EPHA8_HUMAN (663-1323): 1.14e-174: 548: 22.59
+	Hs
		872517 RAB2A_HUMAN (2-187): 1.8e-83: 248: 89.95		EPHB4_HUMAN (662-1321): 3.03e-170: 536: 24.96
+	Hs
		665193 RAB2A_HUMAN (2-187): 1.8e-83: 248: 89.95		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		665197 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		591744 RAB4A_HUMAN (7-168): 9.77e-65: 200: 60.49		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		666646 RAB1B_HUMAN (2-192): 4.11e-85: 251: 41.75		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		666630 RAB1C_HUMAN (2-192): 2.29e-82: 244: 41.75		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		384608 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		609444 RAB2B_HUMAN (2-200): 2.72e-84: 250: 76.08		FGFR3_HUMAN (1016-1288): 2.88e-60: 224: 40.07
+	Hs
		338247 RAB1A_HUMAN (2-192): 3.79e-86: 254: 42.78		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		338238 RB11A_HUMAN (2-196): 2.19e-81: 242: 43.35		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		383971 RAB1B_HUMAN (2-192): 4.11e-85: 251: 41.75		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83
+	Hs
		337921 RAB4A_HUMAN (7-168): 9.77e-65: 200: 60.49		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50