HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 25960396, 27678051, 29180619, 31048496, 31059647, 33188014, 21857666, 15707587, 24656128, 24882209, 24714598
Identification Methods enzymatic study, pull down, affinity chromatography technology, x-ray crystallography, fluorescent resonance energy transfer, x ray scattering
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2
Common GO terms GO:0003677 - DNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 20 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 190
Hs

1 190
+ Rn
+ Mm
+ Hs
+ Hs
+ Zm
+ Hs
+ Dm
+ Sc
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024