HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: SHPS1 (P78324)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
Gene: SIRPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 504
+	Hs
		941147 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		CADM3_HUMAN (22-414): 6.33e-60: 204: 20.51
+	Hs
		941194 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		CADM4_HUMAN (38-426): 3.78e-56: 194: 16.92
+	Hs
		940878 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		CD166_HUMAN (1-312): 3.34e-54: 193: 18.62
+	Hs
		941397 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		CADM1_HUMAN (41-289): 2.77e-25: 109: 21.18
+	Hs
		941309 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		KIRR1_HUMAN (150-493): 1.89e-21: 100: 12.68