HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: PATZ1 (Q9HBE1)
POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)
Gene: PATZ1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	10713105, 11719514
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 687
+	Hs
		1089384 LONF1_HUMAN (15-189): 7.63e-31: 119: 18.08		PATZ1_HUMAN (1-687): 0: 628: 100.00
+	Hs
		941120 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN227_HUMAN (74-632): 0: 565: 21.12
+	Hs
		941352 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN184_HUMAN (48-573): 4.46e-177: 524: 15.74
+	Hs
		67423 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN850_HUMAN (222-687): 6.04e-171: 519: 21.67
+	Hs
		563763 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZNF28_HUMAN (113-687): 2.18e-164: 491: 17.47
+	Hs
		941023 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN658_HUMAN (123-687): 1.12e-153: 473: 15.04
+	Hs
		941453 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN160_HUMAN (48-524): 9.85e-155: 469: 18.41
+	Hs
		563297 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZNF16_HUMAN (48-467): 1.12e-128: 397: 17.02
+	Hs
		549149 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN250_HUMAN (393-655): 6.02e-90: 293: 23.51
+	Hs
		880239 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		MAZ_HUMAN (350-503): 1.98e-70: 238: 70.13
+	Hs
		941201 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN420_HUMAN (72-346): 6.63e-58: 209: 9.97
+	Hs
		941306 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN845_HUMAN (55-319): 6.29e-51: 193: 12.87
+	Hs
		941159 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN808_HUMAN (47-269): 1.11e-31: 134: 7.62
+	Hs
		941171 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZFP62_HUMAN (47-241): 1.52e-23: 108: 7.69
+	Hs
		941407 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN436_HUMAN (294-466): 7.28e-19: 92: 35.26
+	Hs
		941165 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN283_HUMAN (168-352): 4.62e-16: 84.3: 10.97
+	Hs
		940885 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		VEZF1_HUMAN (413-519): 2.07e-11: 68.9: 34.51
+	Hs
		941546 RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00		ZN629_HUMAN (162-379): 3.72e-09: 61.9: 14.59