HitPredict

Interactor 1: SHPS1 (P78324)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
Gene: SIRPA

Interactor 2: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 431
+	Hs
		280561 SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00		KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53
+	Hs
		580011 SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00		K1C15_HUMAN (88-401): 4.65e-95: 295: 52.38
+	Hs
		941694 SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23
+	Hs
		353599 IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89		K1C14_HUMAN (87-400): 4.31e-146: 425: 53.82
+	Hs
		353619 IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89		K1C16_HUMAN (85-412): 2.56e-96: 298: 51.52
+	Hs
		1061304 OPCM_HUMAN (136-453): 8.28e-27: 112: 9.97		K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00
+	Hs
		66240 A8K0Y0_HUMAN (136-453): 8.28e-27: 112: 9.97		K1C40_HUMAN (1-431): 4.93e-84: 265: 100.00
+	Hs
		353629 IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89		K2C5_HUMAN (57-410): 3.29e-75: 247: 25.91
+	Hs
		353600 IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89		K2C6A_HUMAN (57-424): 5.36e-75: 246: 25.20