HitPredict

Interactor 1: ADAM8 (P78325)
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM 8) (EC 3.4.24.-) (Cell surface antigen MS2) (CD antigen CD156a)
Gene: ADAM8

Interactor 2: FBP1L (Q5T0N5)
Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
Gene: FNBP1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25825872
Identification Methods	phage display, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 605
+	Hs
		941717 ADAM8_HUMAN (1-824): 0: 633: 100.00		FNBP1_HUMAN (1-605): 1.1e-101: 323: 53.96
+	Hs
		941711 ADAM8_HUMAN (1-824): 0: 633: 100.00		CIP4_HUMAN (1-599): 1.04e-94: 304: 50.58
+	Hs
		1132434 ADA19_HUMAN (28-824): 2.25e-144: 451: 33.07		FBP1L_HUMAN (1-605): 9.46e-125: 382: 100.00
+	Hs
		1034743 ADAM9_HUMAN (24-723): 4.42e-157: 480: 30.77		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		197625 ADA12_HUMAN (23-824): 7.76e-150: 464: 34.24		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		1034780 ADA15_HUMAN (22-808): 1.19e-124: 397: 30.82		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Mm
		1142117 ADAM9_MOUSE (7-768): 2.35e-158: 484: 30.86		PACN3_MOUSE (188-595): 1.05e-18: 90.7: 11.49
+	Hs
		1356560 ADA18_HUMAN (24-658): 2.06e-111: 358: 25.41		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Mm
		292358 ADA15_MOUSE (54-795): 4.47e-111: 361: 30.09		PACN3_MOUSE (188-595): 1.05e-18: 90.7: 11.49
+	Hs
		152352 ADA10_HUMAN (63-508): 1.87e-23: 108: 24.91		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		944529 ADA17_HUMAN (106-530): 1.19e-20: 99.8: 25.45		PACN3_HUMAN (4-311): 2.21e-63: 216: 14.38
+	Hs
		152353 ADA10_HUMAN (63-508): 1.87e-23: 108: 24.91		PACN2_HUMAN (303-595): 6.96e-20: 94.9: 12.50
+	Hs
		152327 ADA10_HUMAN (63-508): 1.87e-23: 108: 24.91		PACN1_HUMAN (187-595): 2.32e-18: 89.9: 11.86
+	Hs
		944531 ADA17_HUMAN (106-530): 1.19e-20: 99.8: 25.45		PACN2_HUMAN (303-595): 6.96e-20: 94.9: 12.50
+	Hs
		152206 ADA10_HUMAN (63-508): 1.87e-23: 108: 24.91		PPIP1_HUMAN (204-597): 1.35e-16: 84.1: 11.69
+	Hs
		944521 ADA17_HUMAN (106-530): 1.19e-20: 99.8: 25.45		PACN1_HUMAN (187-595): 2.32e-18: 89.9: 11.86
+	Hs
		152211 ADA10_HUMAN (63-508): 1.87e-23: 108: 24.91		GAS7_HUMAN (11-283): 6.14e-15: 79.6: 18.61