Interactor 1: ASIC1 (P78348)
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)
Gene: ASIC1

Interactor 2: ASIC2 (Q16515)
Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG)
Gene: ASIC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ASC~ASC
Common GO terms GO:0005886 - plasma membrane
GO:0015280 - ligand-gated sodium channel activity
GO:0022839 - monoatomic ion-gated channel activity
GO:0035725 - sodium ion transmembrane transport
GO:0042391 - regulation of membrane potential
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 528
Hs

1 512
+ Mm
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024