HitPredict

Interactor 1: ASIC1 (P78348)
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)
Gene: ASIC1

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.677

Property	Details
Experiments	12578970, 11802773, 33961781
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 528 Hs			1 415
+	Rn
		1144090 ASIC2_RAT (1-528): 0: 547: 65.72		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1082097 ASIC2_HUMAN (1-528): 0: 546: 65.91		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Mm
		1143300 ASIC2_MOUSE (1-528): 0: 547: 65.91		PICK1_MOUSE (1-415): 0: 584: 94.47