HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: DLGP2 (Q9P1A6)
Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2)
Gene: DLGAP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	9115257
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 1054
+	Mm
		1143394 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP2_MOUSE (1-1054): 0: 1497: 89.14
+	Rn
		677776 DLG4_RAT (1-724): 0: 668: 99.86		DLGP2_RAT (1-1054): 0: 1482: 89.14
+	Hs
		145945 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP1_HUMAN (80-1054): 0: 1202: 52.16
+	Rn
		677775 DLG4_RAT (1-724): 0: 668: 99.86		DLGP1_RAT (80-1054): 0: 1184: 51.11
+	Mm
		1143504 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP1_MOUSE (80-1054): 0: 1180: 51.11
+	Mm
		936189 DLG3_MOUSE (20-724): 0: 583: 64.08		DLGP1_MOUSE (80-1054): 0: 1180: 51.11
+	Hs
		327234 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP3_HUMAN (80-1054): 0: 1074: 45.72
+	Mm
		1143344 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP3_MOUSE (80-1054): 0: 1042: 45.39
+	Rn
		677777 DLG4_RAT (1-724): 0: 668: 99.86		DLGP3_RAT (80-1054): 0: 1041: 44.81
+	Hs
		1132899 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		DLGP2_HUMAN (1-1054): 0: 1549: 100.00
+	Hs
		4618 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		A0A1B0GTN4_HUMAN (5-1054): 0: 1540: 99.91
+	Hs
		942402 DLG4_HUMAN (1-724): 0: 667: 100.00		DLGP4_HUMAN (80-1054): 0: 955: 42.72
+	Mm
		69918 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP4_MOUSE (80-1054): 0: 931: 41.99
+	Rn
		957000 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP2_RAT (1-1054): 0: 1482: 89.14
+	Rn
		677778 DLG4_RAT (1-724): 0: 668: 99.86		DLGP4_RAT (80-1054): 0: 908: 41.55
+	Rn
		956989 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP1_RAT (80-1054): 0: 1184: 51.11
+	Rn
		957005 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP3_RAT (80-1054): 0: 1041: 44.81
+	Hs
		1132902 MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50		DLGP4_HUMAN (80-1054): 0: 955: 42.72
+	Rn
		957008 DLG1_RAT (143-465): 5.52e-20: 97.1: 20.97		DLGP4_RAT (80-1054): 0: 908: 41.55
+	Mm
		1143445 DLG4_MOUSE (1-724): 0: 667: 99.59		DLGP5_MOUSE (616-1050): 1.13e-58: 219: 18.79