Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Interactor 2: YTDC1 (Q96MU7)
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)
Gene: YTHDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.690

The method score is based on:

Property Details
Experiments 33961781, 32707033, 23602568
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, pull down, anti tag coimmunoprecipitation, tandem affinity purification, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0048024 - regulation of mRNA splicing, via spliceosome
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 688
Hs

1 727
+ Hs
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+ Dm

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Last updated: 15 Jul 2024