HitPredict

Interactor 1: PHC1 (P78364)
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)
Gene: PHC1

Interactor 2: Q5T8Z6 (Q5T8Z6)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1004 Hs			1 105
+	Hs
		717684 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		BMI1_HUMAN (1-105): 9.49e-35: 122: 100.00
+	Hs
		718390 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF2_HUMAN (1-105): 6.67e-34: 121: 90.48
+	Hs
		943088 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF6_HUMAN (2-103): 3.31e-31: 114: 51.96
+	Hs
		943087 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF1_HUMAN (2-103): 6.62e-31: 111: 58.82
+	Mm
		639473 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		BMI1_MOUSE (1-105): 1.41e-34: 122: 100.00
+	Hs
		943064 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF3_HUMAN (4-103): 1.99e-27: 101: 51.00
+	Hs
		943084 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		RING2_HUMAN (7-97): 6.58e-26: 100: 27.17
+	Hs
		943070 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF5_HUMAN (1-100): 3.27e-26: 99.3: 46.00
+	Mm
		620786 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		PCGF2_MOUSE (1-105): 1.95e-32: 117: 90.48
+	Hs
		943060 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		RING1_HUMAN (1-99): 5.64e-25: 98.1: 27.72
+	Mm
		1144863 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		RING2_MOUSE (7-97): 5.99e-26: 100: 27.17
+	Hs
		554277 MUC1_HUMAN (5-886): 1.17e-47: 187: 9.75		BMI1_HUMAN (1-105): 9.49e-35: 122: 100.00
+	Mm
		639480 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		BMI1_MOUSE (1-105): 1.41e-34: 122: 100.00
+	Mm
		620794 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		PCGF2_MOUSE (1-105): 1.95e-32: 117: 90.48
+	Mm
		1321743 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		RING2_MOUSE (7-97): 5.99e-26: 100: 27.17
+	Mm
		193416 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		RING1_MOUSE (1-99): 1.13e-25: 100: 27.72
+	Dm
		627168 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		SUZ2_DROME (1-105): 4.58e-30: 113: 37.38
+	Dm
		728804 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		PSC_DROME (3-102): 3.67e-28: 108: 50.00
+	Dm
		1341979 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		Q9VV77_DROME (4-103): 1.27e-26: 99.3: 54.00
+	Dm
		1341975 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		RING1_DROME (7-97): 7.25e-22: 90: 27.17