HitPredict

Interactor 1: PHC1 (P78364)
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)
Gene: PHC1

Interactor 2: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1004 Hs			1 256
+	Hs
		717684 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38
+	Hs
		718390 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13
+	Mm
		639473 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		BMI1_MOUSE (1-229): 1.41e-56: 185: 30.21
+	Hs
		943064 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04
+	Mm
		620786 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		PCGF2_MOUSE (1-244): 1.85e-53: 177: 28.35
+	Hs
		943088 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25
+	Hs
		943084 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		RING2_HUMAN (2-252): 1.71e-41: 146: 17.59
+	Hs
		943087 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06
+	Hs
		943066 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		Q5T8Z6_HUMAN (1-104): 6.49e-44: 145: 44.23
+	Hs
		943060 PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00		RING1_HUMAN (2-142): 1.22e-34: 129: 20.42
+	Mm
		1144863 PHC1_MOUSE (1-1004): 1.64e-80: 284: 91.58		RING2_MOUSE (2-252): 2.64e-41: 146: 17.59
+	Hs
		554277 MUC1_HUMAN (5-886): 1.17e-47: 187: 9.75		BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38
+	Mm
		639480 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		BMI1_MOUSE (1-229): 1.41e-56: 185: 30.21
+	Mm
		620794 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		PCGF2_MOUSE (1-244): 1.85e-53: 177: 28.35
+	Mm
		1321743 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		RING2_MOUSE (2-252): 2.64e-41: 146: 17.59
+	Dm
		627168 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		SUZ2_DROME (9-226): 2.21e-46: 167: 26.13
+	Dm
		728804 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		PSC_DROME (2-252): 3.97e-46: 166: 25.39
+	Mm
		193416 PHC2_MOUSE (186-1004): 2.37e-44: 175: 22.38		RING1_MOUSE (2-142): 1.03e-35: 133: 20.42
+	Dm
		1341979 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		Q9VV77_DROME (3-222): 1.49e-44: 151: 41.26
+	Dm
		1341975 Q9NF31_DROME (410-1003): 2.44e-34: 145: 19.97		RING1_DROME (2-124): 2.24e-31: 121: 26.61