HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	33961781, 29531219, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 396
+	Hs
		1028020 TCPH_HUMAN (4-532): 0: 591: 34.08		ERCC8_HUMAN (1-396): 7.48e-87: 270: 100.00
+	Hs
		1306645 TCPH_HUMAN (4-532): 0: 591: 34.08		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		943437 TCPB_HUMAN (1-535): 0: 586: 100.00		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		943393 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (128-395): 4.9e-60: 208: 13.76
+	Hs
		943403 TCPB_HUMAN (1-535): 0: 586: 100.00		SNR40_HUMAN (140-394): 5.23e-55: 186: 13.41
+	Hs
		903467 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		903120 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		1202777 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		943328 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		943370 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		1240450 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		943355 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		1306704 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (3-71): 4.91e-16: 81.3: 18.57
+	Hs
		1083362 TCPH_HUMAN (4-532): 0: 591: 34.08		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		943508 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (3-71): 4.91e-16: 81.3: 18.57
+	Hs
		943246 TCPB_HUMAN (1-535): 0: 586: 100.00		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		1017427 TCPH_HUMAN (4-532): 0: 591: 34.08		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		197078 TCPH_HUMAN (4-532): 0: 591: 34.08		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Hs
		943205 TCPB_HUMAN (1-535): 0: 586: 100.00		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		197001 TCPB_HUMAN (1-535): 0: 586: 100.00		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27