HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 347
+	Hs
		1038670 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Mm
		945920 TCPH_MOUSE (4-534): 0: 599: 33.77		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		943219 TCPB_HUMAN (1-535): 0: 586: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		826651 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		177367 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		826813 TCPG_HUMAN (3-532): 0: 561: 28.33		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Hs
		177257 TCPB_HUMAN (1-535): 0: 586: 100.00		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Mm
		945965 TCPE_MOUSE (8-524): 0: 554: 32.64		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Sc
		693016 TCPB_YEAST (9-532): 0: 566: 65.71		RPD3_YEAST (2-340): 1.99e-131: 383: 22.95
+	Sc
		693035 TCPH_YEAST (1-532): 0: 559: 33.09		RPD3_YEAST (2-340): 1.99e-131: 383: 22.95
+	Hs
		826803 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177233 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Sc
		760656 TCPB_YEAST (9-532): 0: 566: 65.71		HOS2_YEAST (3-331): 6.58e-124: 365: 21.43
+	Sc
		792389 TCPH_YEAST (1-532): 0: 559: 33.09		HOS2_YEAST (3-331): 6.58e-124: 365: 21.43
+	Hs
		177231 TCPE_HUMAN (1-528): 0: 541: 32.29		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		1306720 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		943524 TCPB_HUMAN (1-535): 0: 586: 100.00		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		826927 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Sp
		140638 TCPH_SCHPO (6-533): 0: 576: 33.90		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69
+	Sp
		140519 TCPG_SCHPO (5-526): 0: 559: 26.74		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69