HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: PI3R4 (Q99570)
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)
Gene: PIK3R4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 1358
+	Hs
		1304595 TCPH_HUMAN (4-532): 0: 591: 34.08		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		826838 TCPG_HUMAN (3-532): 0: 561: 28.33		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		573435 TCPA_HUMAN (5-533): 0: 541: 34.30		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		821377 TCPE_HUMAN (1-528): 0: 541: 32.29		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		148669 TCPB_HUMAN (1-535): 0: 586: 100.00		CTRO_HUMAN (10-864): 4.4e-129: 442: 11.77
+	Hs
		148532 TCPG_HUMAN (3-532): 0: 561: 28.33		CTRO_HUMAN (10-864): 4.4e-129: 442: 11.77
+	Hs
		148376 TCPA_HUMAN (5-533): 0: 541: 34.30		CTRO_HUMAN (10-864): 4.4e-129: 442: 11.77
+	Hs
		148525 TCPE_HUMAN (1-528): 0: 541: 32.29		CTRO_HUMAN (10-864): 4.4e-129: 442: 11.77
+	Hs
		943373 TCPB_HUMAN (1-535): 0: 586: 100.00		MK15_HUMAN (22-335): 6.42e-62: 224: 19.54
+	Hs
		1306702 TCPH_HUMAN (4-532): 0: 591: 34.08		STRN4_HUMAN (956-1272): 7.89e-58: 216: 19.76
+	Hs
		943506 TCPB_HUMAN (1-535): 0: 586: 100.00		STRN4_HUMAN (956-1272): 7.89e-58: 216: 19.76
+	Hs
		826788 TCPG_HUMAN (3-532): 0: 561: 28.33		MK15_HUMAN (22-335): 6.42e-62: 224: 19.54
+	Hs
		826909 TCPG_HUMAN (3-532): 0: 561: 28.33		STRN4_HUMAN (956-1272): 7.89e-58: 216: 19.76
+	Hs
		573500 TCPA_HUMAN (5-533): 0: 541: 34.30		STRN4_HUMAN (956-1272): 7.89e-58: 216: 19.76
+	Hs
		821434 TCPE_HUMAN (1-528): 0: 541: 32.29		STRN4_HUMAN (956-1272): 7.89e-58: 216: 19.76
+	Rn
		506695 TCPA_RAT (7-532): 4.33e-83: 270: 34.85		KCC2A_RAT (24-470): 3.62e-98: 324: 15.35