HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: KTNB1 (Q9BVA0)
Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)
Gene: KATNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 655
+	Hs
		1306654 TCPH_HUMAN (4-532): 0: 591: 34.08		KTNB1_HUMAN (4-655): 0: 559: 100.00
+	Sc
		760660 TCPB_YEAST (9-532): 0: 566: 65.71		COPA_YEAST (1-646): 1.38e-100: 334: 16.03
+	Hs
		197078 TCPH_HUMAN (4-532): 0: 591: 34.08		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		943370 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (1-264): 9.89e-85: 276: 29.06
+	Hs
		197001 TCPB_HUMAN (1-535): 0: 586: 100.00		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		943393 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		196973 TCPG_HUMAN (3-532): 0: 561: 28.33		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		1306704 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Hs
		943508 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Dm
		1001754 Q9W392_DROME (4-535): 0: 568: 70.73		Q0KHS0_DROME (384-648): 4.27e-40: 159: 23.22
+	Hs
		943403 TCPB_HUMAN (1-535): 0: 586: 100.00		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		1240450 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (1-91): 2.44e-19: 92.8: 21.98
+	Hs
		943355 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (1-91): 2.44e-19: 92.8: 21.98
+	Hs
		792942 TCPG_HUMAN (3-532): 0: 561: 28.33		LIS1_HUMAN (227-420): 5.51e-27: 115: 14.29
+	Hs
		267753 TCPB_HUMAN (1-535): 0: 586: 100.00		TAF5L_HUMAN (36-139): 7.24e-15: 80.1: 35.58
+	Hs
		903467 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		1202777 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (261-467): 3.81e-12: 70.1: 7.66
+	Hs
		903120 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		943328 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (261-467): 3.81e-12: 70.1: 7.66
+	Hs
		826601 TCPG_HUMAN (3-532): 0: 561: 28.33		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33