HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: MLP3A (Q9H492)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)
Gene: MAP1LC3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	35366418, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 121
+	Hs
		1306679 TCPH_HUMAN (4-532): 0: 591: 34.08		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		891285 TCPH_HUMAN (4-532): 0: 591: 34.08		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		1306669 TCPH_HUMAN (4-532): 0: 591: 34.08		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		891072 TCPB_HUMAN (1-535): 0: 586: 100.00		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		306102 TCPB_HUMAN (1-535): 0: 586: 100.00		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		943468 TCPB_HUMAN (1-535): 0: 586: 100.00		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		943457 TCPB_HUMAN (1-535): 0: 586: 100.00		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		943476 TCPB_HUMAN (1-535): 0: 586: 100.00		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Sc
		745987 TCPB_YEAST (9-532): 0: 566: 65.71		ATG8_YEAST (3-120): 2.38e-54: 167: 35.59
+	Hs
		826883 TCPG_HUMAN (3-532): 0: 561: 28.33		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		826592 TCPG_HUMAN (3-532): 0: 561: 28.33		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		826873 TCPG_HUMAN (3-532): 0: 561: 28.33		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		826864 TCPG_HUMAN (3-532): 0: 561: 28.33		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		826877 TCPG_HUMAN (3-532): 0: 561: 28.33		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05
+	Hs
		821407 TCPE_HUMAN (1-528): 0: 541: 32.29		MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00
+	Hs
		573193 TCPA_HUMAN (5-533): 0: 541: 34.30		GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74
+	Hs
		305955 TCPA_HUMAN (5-533): 0: 541: 34.30		GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44
+	Hs
		573465 TCPA_HUMAN (5-533): 0: 541: 34.30		MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82
+	Hs
		573461 TCPA_HUMAN (5-533): 0: 541: 34.30		MLP3C_HUMAN (1-120): 5.63e-51: 159: 59.17
+	Hs
		573470 TCPA_HUMAN (5-533): 0: 541: 34.30		GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05