HitPredict

Interactor 1: KRT85 (P78386)
Keratin, type II cuticular Hb5 (Hair keratin K2.12) (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)
Gene: KRT85

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 Hs			1 768
+	Hs
		380606 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		409064 K2C8_HUMAN (46-461): 7.91e-114: 346: 53.61		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042632 KRT84_HUMAN (1-506): 2.9e-107: 333: 56.73		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		318804 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041699 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		380607 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		380608 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		943670 KRT85_HUMAN (1-507): 4.34e-118: 358: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		943671 KRT85_HUMAN (1-507): 4.34e-118: 358: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		380604 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		318805 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		318806 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		380605 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1043388 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		318802 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		517775 K2C3_HUMAN (95-434): 2.72e-128: 388: 58.14		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		380662 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		318803 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041347 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		318858 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL5_HUMAN (25-768): 0: 597: 23.77