HitPredict

Interactor 1: KRT85 (P78386)
Keratin, type II cuticular Hb5 (Hair keratin K2.12) (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)
Gene: KRT85

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32235678
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 Hs			1 759
+	Hs
		380607 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		380608 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		943671 KRT85_HUMAN (1-507): 4.34e-118: 358: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		318805 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		318806 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043388 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		380606 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		943669 KRT85_HUMAN (1-507): 4.34e-118: 358: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		409064 K2C8_HUMAN (46-461): 7.91e-114: 346: 53.61		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042632 KRT84_HUMAN (1-506): 2.9e-107: 333: 56.73		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		380604 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		318804 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		380605 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		1041699 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		318802 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		318803 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		517775 K2C3_HUMAN (95-434): 2.72e-128: 388: 58.14		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Hs
		1041347 K2C71_HUMAN (3-505): 3.44e-82: 266: 42.16		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		380662 K2C1_HUMAN (92-448): 8.37e-123: 375: 54.44		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Hs
		318858 K2C75_HUMAN (3-437): 4.67e-87: 279: 49.78		CUL5_HUMAN (59-759): 0: 589: 24.94