HitPredict

Interactor 1: RAE1L (P78406)
mRNA export factor RAE1 (Rae1 protein homolog) (mRNA-associated protein mrnp 41)
Gene: RAE1

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 368 Hs			1 513
+	Hs
		943901 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		792949 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		LIS1_HUMAN (4-472): 9.67e-90: 282: 15.13
+	Hs
		245633 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		1309163 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		TBL1Y_HUMAN (252-512): 1.12e-61: 212: 18.02
+	Hs
		245546 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		TBL1X_HUMAN (252-512): 3.08e-62: 215: 18.38
+	Hs
		245630 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		TBL1Y_HUMAN (252-512): 1.12e-61: 212: 18.02
+	Hs
		903551 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903077 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Sp
		999842 TUP11_SCHPO (67-366): 2.41e-66: 222: 12.96		TUP12_SCHPO (4-245): 2.78e-20: 96.2: 10.98
+	Sp
		999838 TUP11_SCHPO (67-366): 2.41e-66: 222: 12.96		TUP11_SCHPO (209-378): 4.49e-12: 70.5: 26.92
+	Sc
		630844 NLE1_YEAST (117-366): 6.81e-45: 163: 9.40		NLE1_YEAST (440-513): 1.34e-20: 96.9: 25.33
+	Hs
		1240442 POC1B_HUMAN (2-159): 3.19e-39: 147: 21.30		POC1A_HUMAN (436-513): 5.31e-19: 91.2: 19.23
+	Hs
		1346954 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46
+	Hs
		929579 POC1B_HUMAN (2-159): 3.19e-39: 147: 21.30		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		921751 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		GBB2_HUMAN (187-335): 1.43e-21: 97.7: 20.81
+	Hs
		929692 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		903109 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		903174 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		TBL3_HUMAN (213-376): 4.84e-09: 60.8: 24.55