Interactor 1: KCJ10 (P78508)
ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10)
Gene: KCNJ10

Interactor 2: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0005242 - inward rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport
GO:0034702 - monoatomic ion channel complex
GO:0034765 - regulation of monoatomic ion transmembrane transport
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 379
Hs

1 433
+ Gg
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024