Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: CIB1 (Q99828)
Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28)
Gene: CIB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.55 0.581

The method score is based on:

Property Details
Experiments 9372844, 15190070
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006302 - double-strand break repair
GO:0006974 - DNA damage response
and 2 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024