Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: PAXX (Q9BUH6)
Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein)
Gene: PAXX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.55 0.547

The method score is based on:

Property Details
Experiments 30017584, 31548606
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006974 - DNA damage response
GO:0070419 - nonhomologous end joining complex
Homologous interactions 0

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Last updated: 15 Jul 2024