HitPredict

Interactor 1: ADA17 (P78536)
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)
Gene: ADAM17

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.662

The method score is based on:

Property Details
Experiments 12668732, 18930083
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid pooling approach, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0016324 - apical plasma membrane
and 1 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 824
Hs

1 904
+ Hs
+ Mm
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+ Dm
+ Hs
+ Mm
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024