Interactor 1: BTG2 (P78543)
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)
Gene: BTG2

Interactor 2: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 25416956, 32296183, 29395067, 11136725, unassigned1304
Identification Methods two hybrid, proximity labelling technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTG~CAF1
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 158
Hs

1 285
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Last updated: 15 Jul 2024