HitPredict

Interactor 1: RED1 (P78563)
Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)
Gene: ADARB1

Interactor 2: STAU2 (Q9NUL3)
Double-stranded RNA-binding protein Staufen homolog 2
Gene: STAU2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	A_deamin~dsrm, dsrm~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0003729 - mRNA binding GO:0005730 - nucleolus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 741 Hs			1 570
+	Hs
		269692 RED1_HUMAN (1-741): 0: 850: 100.00		PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69
+	Hs
		322475 RED1_HUMAN (1-741): 0: 850: 100.00		STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33
+	Hs
		585441 RED1_HUMAN (1-741): 0: 850: 100.00		E2AK2_HUMAN (10-212): 2.07e-26: 115: 21.46
+	Hs
		944735 RED1_HUMAN (1-741): 0: 850: 100.00		RED1_HUMAN (306-423): 3.65e-19: 93.5: 27.50
+	Hs
		877238 RED1_HUMAN (1-741): 0: 850: 100.00		DSRAD_HUMAN (6-184): 4.38e-18: 90.4: 19.47
+	Hs
		944959 RED1_HUMAN (1-741): 0: 850: 100.00		RED2_HUMAN (306-415): 1.51e-15: 82: 21.43
+	Hs
		944801 RED1_HUMAN (1-741): 0: 850: 100.00		TRBP2_HUMAN (294-466): 8.5e-16: 81.2: 15.64
+	Hs
		944763 RED1_HUMAN (1-741): 0: 850: 100.00		ILF3_HUMAN (274-428): 1.06e-11: 70: 21.38
+	Hs
		944902 RED1_HUMAN (1-741): 0: 850: 100.00		STRBP_HUMAN (178-374): 1.87e-11: 68.9: 19.70
+	Hs
		269745 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		PRKRA_HUMAN (2-273): 4.61e-41: 152: 18.69
+	Dm
		1367119 SON_DROME (27-302): 1.46e-47: 183: 19.44		LOQS_DROME (7-379): 6.2e-34: 136: 16.20
+	Hs
		322682 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		STAU1_HUMAN (6-395): 1.38e-29: 125: 17.33
+	Hs
		585482 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		E2AK2_HUMAN (10-212): 2.07e-26: 115: 21.46
+	Dm
		1228909 Q8MRC7_DROME (2-300): 3.81e-57: 201: 24.14		ADAR_DROME (83-256): 2.52e-16: 84.2: 11.50
+	Hs
		877283 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		DSRAD_HUMAN (6-184): 4.38e-18: 90.4: 19.47
+	Rn
		88578 D3ZDD7_RAT (23-280): 4.63e-48: 182: 36.23		E2AK2_RAT (309-418): 9.67e-17: 85: 24.32
+	Hs
		1075596 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		TRBP2_HUMAN (294-466): 8.5e-16: 81.2: 15.64
+	Hs
		1019762 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		ILF3_HUMAN (274-428): 1.06e-11: 70: 21.38