HitPredict

Interactor 1: DRB3 (P79483)
HLA class II histocompatibility antigen, DR beta 3 chain (MHC class II antigen DRB3)
Gene: HLA-DRB3

Interactor 2: I27RA (Q6UWB1)
Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)
Gene: IL27RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 266 Hs			1 636
+	Hs
		382457 HLAA_HUMAN (34-256): 3.89e-90: 273: 20.35		I27RA_HUMAN (1-636): 7.04e-114: 356: 100.00
+	Hs
		354491 HLAB_HUMAN (34-233): 4.03e-79: 244: 20.69		I27RA_HUMAN (1-636): 7.04e-114: 356: 100.00
+	Hs
		488267 HLAC_HUMAN (39-228): 9.55e-65: 208: 22.56		I27RA_HUMAN (1-636): 7.04e-114: 356: 100.00
+	Hs
		382507 HLAA_HUMAN (34-256): 3.89e-90: 273: 20.35		I12R2_HUMAN (32-635): 6.52e-81: 274: 21.20
+	Hs
		234461 HLAA_HUMAN (34-256): 3.89e-90: 273: 20.35		DSCAM_HUMAN (115-326): 1.42e-16: 86.4: 14.09
+	Hs
		789676 HFE_HUMAN (58-237): 3.41e-11: 64.3: 26.34		LIFR_HUMAN (32-568): 3.4e-85: 290: 17.28
+	Hs
		588768 DPA1_HUMAN (120-256): 1.6e-12: 67.4: 28.38		PTPRS_HUMAN (14-631): 8.1e-48: 183: 10.80
+	Hs
		629199 ZA2G_HUMAN (58-219): 2.67e-11: 64.3: 21.34		FND3A_HUMAN (232-635): 1.81e-31: 133: 10.72
+	Hs
		82439 IGLL5_HUMAN (112-215): 1.23e-10: 61.6: 34.55		NEO1_HUMAN (23-235): 7.08e-20: 96.9: 13.64
+	Hs
		82367 IGLL5_HUMAN (112-215): 1.23e-10: 61.6: 34.55		FINC_HUMAN (24-396): 8.68e-20: 96.5: 11.54